INCREASE OF NEUTROPHIL EXTRACELLULAR TRAPS, MITOCHONDRIAL DNA AND NUCLEAR DNA IN NEWLY DIAGNOSED TYPE 1 DIABETES CHILDREN BUT NOT IN HIGH-RISK CHILDREN

Neutrophil extracellular traps (NETs) and mitochondrial DNA (mtDNA) are inflammatory mediators involved in the development of type 1 diabetes (T1D).Pancreas-infiltrating neutrophils can release NETs, contributing to the inflammatory process.Levels of NETs are increased in serum from patients with T1D and mtDNA is increased in adult T1D patients.Our

Insects of the order Orthoptera are well-known for their acoustic communication.The structures used for this purpose show a high diversity which obviously relates to differences in song parameters and to the physics of sound production.Here we describe song and morphology of the sound producing organs of a tropical bush-cricket, Ectomoptera nepicau

Abstract Deregulation of RNA Polymerase II (RNAPII) by oncogenic signaling leads to collisions of RNAPII with DNA synthesis machinery (transcription-replication conflicts, TRCs).TRCs can result in DNA damage and are thought to underlie genomic instability in tumor cells.Here we provide evidence that elongating RNAPII nucleates activation of the ATM

The rapid development of information technology makes a lot of electronic components used in various fields.The component that is often used is a microcontroller.The microcontroller is used as the regulator and the automation system.This study aims to design a microcontroller-based water injection (WAI) system on the motorcycle.The experiment was c

Introduction: The development of a vaccine against Staphylococcus aureus has proven to be much more difficult than expected.In this study, we considered and analyzed a mutant Toxic Shock Syndrome Toxin-1 (TSST-1) as a potential vaccine candidate.Methods: An NCBI sequence of TSST-1 was analyzed bioinformatically by online tools such as Ensemble and